A bench of Justices A M Khanwilkar and Ajay Rastogi which rejected the plea said it had gone through the records and it showed that Shariff was the President of the Bengaluru unit of the PFI and the other accused are also members of the outfit.“It reveals from the chargesheet that there was frequent telephonic/mobile conversation between appellant (accused no. 5) with other accused persons (accused nos. 1 to 4) prior and subsequent to16th October, 2016 (the alleged date of incident) which persuaded the Court to arrive to a conclusion that there is a prima facie material of conspiracy among the accused persons giving rise to sufficient grounds of subjective satisfaction of prima facie case of alleged offences of conspiracy being hatched among the accused persons and truth & veracity of such conspiracy is to be examined during the course of trial”, the court said.According to the complaint in the case, Rudresh was hacked by the accused who was riding pillion on a motorcycle near Srinivas Medical Stores in Shivajinagar at around 12.40 pm. The accused fled the scene after that Rudresh was taken to a hospital where he was declared brought dead. PFI mouthpiece Thejas to stop publication this year By Express News Service |New Delhi | Updated: July 2, 2019 7:11:05 am A bench comprising Justices A M Khanwilkar and Ajay Rastogi dismissed the petitionThe Supreme Court Monday dismissed a plea by Popular Front of India leader (PFI) Asim Shariff against the framing of charges against him for the alleged murder of RSS worker Rudresh in Bengaluru in October 2016. Student killing: Kerala police to seek legal opinion on invoking UAPA Jharkhand High Court sets aside ban on PFI Advertising Advertising Related News Initially, four accused persons (accused nos. 1 to 4) werearrested on October 27, 2016. accused no. 5 (Shariff) was arrested on November 2, 2016. Subsequently, the probe was handed over to the National Investigating Agency (NIA) on December 7, 2016.NIA registered FIR against all five accused and after investigation, submitted chargesheet against them in April 2017 stating that the accused 1-4 conspired with the accused number 5 to kill RSS members and in furtherance of their acts, they committed offence punishable under the Indian Penal Code. The accused persons were said to be in possession of weapons without license, thereby it attracted the offence punishable under Sections 3 and 27 of the Arms Act.The appellant and other accused persons sought discharge but this was rejected and charges were framed agaisnt them. This was upheld by the High Court.Upholding this, the SC said “after going through the records and the judgment impugnedbefore us, in the present facts and circumstances, we find no error in the judgment passed by the trial Court and confirmed by the High Court by the impugned judgment dated 22nd November,2018 which calls for our interference.” 0 Comment(s)
Advertising Govt taking steps to protect indigenous breeds of cow: Giriraj Singh In another initiative, the union government will launch a pilot project in which 10 houses of a village (willing to volunteer) will be given a ‘desi’ hen. The move is aimed to tap into the increased demand of organic eggs in the world, with each family getting around 50-60 eggs which will add to their income.“The biggest problem of the dairy sector is fodder, to decrease its input cost,” he said, adding that his ministry is working on a project to encourage the usage of Quality Protein Maize (QPM) as fodder. They are also planning to bring ‘Saragvo’ (leifera) as fodder.He added that he had been working on the project for the past 10 years in Bihar, and had also written to the Prime Minister in the previous government.Replying to a question on how his ministry will deal with the fodder issue when a significant part of the country is facing rain shortage, Singh said our country is facing a contradiction with floods in some places and droughts in others, and the ministry is dealing with the subject accordingly.“The entire society will have to show concern. The day the entire the society will be a part of the government, people will start understanding,” Singh said, adding that people should give a fair chance to the government which has started its efforts in the direction of doubling farmers’ income. Related News Voting rights of couples with more than two kids must be stripped off: Giriraj Singh Union Minister of Animal Husbandry, Dairying and Fisheries Giriraj Singh (File photo)On a day-long official tour of Gujarat on Sunday, Union Minister of Animal Husbandry, Dairying and Fisheries Giriraj Singh discussed future plans of his ministry to complement Prime Minister Narendra Modi’s target to double farmers’ income, even as he said that one of the major issues the dairy sector currently faces is that of fodder. Giriraj wants couples with more than two children stripped of right to vote Addressing a press conference, Singh said that the PM has, for the first time, created a separate ministry for animal husbandry, dairying and fisheries since it is important for farmers to indulge in livestock along with traditional farming.He said that a number of initiatives are being taken by the Union government for this purpose, for instance, an attempt to increase the cattle’s resistance against deadly diseases like Foot & Mouth Disease (FMD) and Brucellosis, which lowers the productivity of farmers by 30%. “Like Polio (campaign), we will eradicate FMD from the cattle in the next five years…Similarly, we have received funds to eradicate Brucellosis.”The Union minister added that initiatives for the development of breeds are also being taken, such as the control of population of unproductive cattle and improving the breed of milch animals through sex-sorted semen technology, under which a female cattle will give birth to only female calves. He said that, in total, 11 sex-sorted semen laboratories will be started, and three such laboratories with two lakh doses are expected to start their operations next month. Advertising By Express News Service |Gandhinagar | Published: July 15, 2019 5:30:36 am 1 Comment(s)
Karnataka trust vote today: Speaker’s call on resignations, says SC, but gives rebel MLAs a shield Back to the Front Udaipur voted third best city to visit in the world: Here are the top 5 attractions “They pelted stones at police, torched vehicles and blocked the road. SP along with additional policemen rushed to the spot and controlled the situation,” she told PTI.The IG said the situation is tense but under control.The Patel community members were agitating following the killing of a man, Ramesh Patel, and were dissatisfied with police action in the case.An FIR was registered on July 12 after Patel’s body was recovered from a forest area. Nine pilgrims from Gujarat killed in Udaipur Advertising Best Of Express A police inspector received head injury and a civilian was also among those injured in the violence in Jawar area, nearly 40 km from the Udaipur district headquarter.The protesters damaged several vehicles including two roadways buses and two police vehicles. They pelted stones at police personnel and blocked a road in the area.IG Udaipur Binita Thakur said a delegation from the community wanted to make a representation to senior officials at the district headquarter, but they resorted to violence. Advertising Police arrested two accused, Ramesh Meena and Paras Meena, but Patel’s family members and relatives demand that other suspects too be arrested.“As per the primary investigation, police found the involvement of two men and they were arrested. The family and other men from their side want to name some other persons as accused and were demanding their arrest,” Thakur said. By PTI |Udaipur | Published: July 15, 2019 8:18:02 pm After Masood Azhar blacklisting, more isolation for Pakistan Post Comment(s) Cabinet asks finance panel to consider securing funds for defence Related News The Patel community members were agitating following the killing of a man, Ramesh Patel, and were dissatisfied with police action in the case. (Representative Image)Dissatisfied with the investigation into a murder case, Patel community members pelted stones, torched vehicles and blocked a road in Udaipur district of Rajasthan Monday, injuring several police personnel, including a woman constable, an official said.
A wide variety of lighting effects that mimic real life can be rendered with Turing that in the past were just too resource-intensive to create in real time.”You’re moving from a painting to a photograph in terms of rendering quality,” said Daniel Wong, professor of electrical and computer engineering at the University of California, Riverside.”It will allow game developers to create more photorealistic games,” he told TechNewsWorld.”Now when you play a virtual reality game, you know you’re in a video game. With ray tracing, everything looks real because light is bouncing around as it does in real life,” Wong explained. “It will be possible in the future, with ray tracing, for you not to be able to tell the difference between the virtual reality world and the real world.” Worth the Expense Nvidia’s initial Turing-based products are the Quadro RTX 8000 ($10,000), Quadro RTX 6000 ($6,300) and Quadro RTX 5000 ($2,300). They’re expected to be available in the fourth quarter.Despite the high price tags, they are in a class by themselves when it comes to performance and capabilities, suggested Anshel Sag, an analyst at Austin, Texas-based Moor Insights & Strategy, in a Forbes post.No other GPU can render complex ray-traced scenes in real time with just one GPU, which is something the RTX 8000 can do, he added.Even the best technology is irrelevant if no one uses it. Nvidia appears to have that base covered, though. With the Turing announcement it revealed pledges of support for the new architecture from developers of key graphics applications used by millions of designers, artists and scientists.Those applications include Adobe Dimension CC, Autodesk Arnold, Clarisse, DaVinci Resolve, Dassault Systemes Catia and Solidworks, Octane Render, ParaView, Redshift, Siemens NX, Unity and Unreal Engine.The companies’ support is a good indication that RTX will thrive, noted Sag. Nvidia Turing Dieshot Nvidia on Monday announced a powerful new graphics architecture with the potential to blur the line between virtual and actual reality. Nvidia CEO Jensen Huang unveiled the new chips at the company’s SIGGRAPH 2018 event in Vancouver, Canada.The Turing architecture enables a new generation of hybrid rendering that can be used to create cinematic-quality interactive experiences, effects powered by neural networks, and fluid interactivity on highly complex models. Engines of Mass Rendering Aimed at the US$250 billion visual effects industry, Turing combines two engines to make real-time ray tracing possible. Its RT Cores accelerate ray tracing, while its Tensor Cores are used for AI referencing.The RT Cores are dedicated ray-tracing processors that accelerate light and sound travel in 3D environments to up to 10 GigaRays a second. Turing accelerates real-time ray tracing operations by up to 25 times that of previous generation chips, Nvidia noted.What’s more, the architecture’s GPU nodes can be used for final-frame rendering for film at more than 30 times the speed of CPU nodes.The Tensor Cores are processors that accelerate deep learning training and inferencing. They’re capable of providing up to 500 trillion tensor operations per second.To help developers take advantage of Turing’s capabilities, Nvidia also introduced a new RTX development platform, which includes artificial intelligence, ray-tracing and simulation software development kits.In addition, it announced the Nvidia NGX software development kit, a deep-learning technology stack to help developers easily integrate accelerated, enhanced graphics, photo imaging and video processing into applications with pretrained networks. John P. Mello Jr. has been an ECT News Network reportersince 2003. His areas of focus include cybersecurity, IT issues, privacy, e-commerce, social media, artificial intelligence, big data and consumer electronics. He has written and edited for numerous publications, including the Boston Business Journal, theBoston Phoenix, Megapixel.Net and GovernmentSecurity News. Email John. There is still an object missing object from the Turing picture.It’s likely that a part for consumer real-time ray-tracing is in the offing, according to Sag.However, access for consumers likely is years away, according to Brett L. Sappington, senior director of research at Parks Associates, a market research and consulting company in Addison, Texas.”This technology is primarily focused on professional graphics use rather than the consumer market,” he told TechNewsWorld.”It could have application in VR, particularly for business use cases. However, it is not likely to be a consumer product for several years,” Sappington said.”Nvidia has shown it’s very good over time at taking these high-end technologies and adapting them to the consumer market,” Technalysis’ O’Donnell told TechNewsWorld. “The challenge with this chip is that it is physically enormous in size, so it may be hard to shrink it down to something consumers can use.” What About Consumers? Holy Grail of Industry “Turing is Nvidia’s most important innovation in computer graphics in more than a decade,” Huang said.”Hybrid rendering will change the industry, opening up amazing possibilities that enhance our lives with more beautiful designs, richer entertainment and more interactive experiences,” he predicted.”The arrival of real-time ray tracing is the Holy Grail of our industry,” added Huang.”This is a significant moment in the history of computer graphics,” said Jon Peddie, CEO of Jon Peddie Research in Tiburon, California. “Nvidia is delivering real-time ray tracing five years before we had thought possible.”All that power Turing promises won’t come cheaply, though.”Some of the cards will cost up to $10,000, but if you do graphics for a living, that has value for you,” observed Bob O’Donnell, chief analyst at Technalysis Research, a technology market research and consulting firm in Foster City, California.
Related StoriesLiver fat biomarker levels linked with metabolic health benefits of exercise, study findsDiet and physical exercise do not reduce risk of gestational diabetesExercise during pregnancy can promote bone health of both mother and childThe November issue of ACSM’s Health & Fitness Journal features articles and columns dedicated to several of the top trends in the 2019 fitness survey, including wearable technology and fitness apps, HIIT, body weight training, and yoga. The special issue also presents four commentaries on the survey findings, authored by internationally recognized experts.Dr. Thompson emphasizes the value of the annual survey in appreciating the differences between trends and fads in the fitness industry – helping to make important investment decisions and programming decisions for future growth and development. The author concludes, “While no one can accurately predict the future of any industry, this survey helps to track trends that can assist owners, operators, program directors, and health fitness professionals with making important business decisions.” Wearable technology returned to the top-ranked position it had occupied for two consecutive years, before dropping to number three in last year’s survey. The return of wearables to number one “may be the result of manufacturers correcting some monitoring inaccuracies of the past,” according to Dr. Thompson. Group training, defined as classes of more than five participants, was rated number two for the second year in a row. This item was recently revised to distinguish it from small group personal training, which was ranked number 19. Rounding out the top five were high-intensity interval training (HIIT), referring to short bouts of high-intensity exercise followed by a short rest period; fitness programs for older adults, which has made a strong return to the top 10 in recent surveys; and body weight training, which uses the person’s own body weight to provide resistance. There’s a growing emphasis on employing certified fitness professionals – certified by ACSM or other nationally accredited organizations. A revised item specifying professional certification ranked sixth in the 2019 survey. An expanded item on worksite health promotion and workplace well-being made its first appearance in the top 20, scoring at number 15. Trends dropping out of the top 20 since the previous survey were circuit weight training, sport-specific training, and core training. Reviewed by James Ives, M.Psych. (Editor)Oct 26 2018Fitness trackers, smart watches, and other wearable technology are the number one fitness trend for 2019, according to an annual survey of health and fitness professionals published in the November issue of ACSM’s Health & Fitness Journal®, an official journal of the American College of Sports Medicine (ACSM). The journal is published in the Lippincott portfolio by Wolters Kluwer.Other notable trends in the 13th annual survey include the continued rise of high-intensity interval training (HIIT), increased interest in hiring certified fitness professionals, and growing interest in workplace health and wellness programs, according to the report by Walter R. Thompson, PhD, FACSM, of Georgia State University, Atlanta, and Immediate Past-President of ACSM. He writes, “The survey was designed to confirm or to introduce new trends (not fads) that have a perceived positive impact on the industry according to the international respondent.”Tracking Trends in the Health Fitness Industry – What’s Hot, What’s NotConducted each year since 2007, the 13th annual survey included responses from more than 2,000 health fitness professionals from around the world. Respondents represented all sectors of the industry: commercial, clinical, community, and corporate.Highlights of the 2019 annual survey of health and fitness trends included: Source:http://home.lww.com/news.entry.html/2018/10/25/wearable_tech_become-juoq.html
Reviewed by Kate Anderton, B.Sc. (Editor)Jan 25 2019Patients undergoing long-term treatment with steroids may suffer from metabolic side effects. Researchers at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich (LMU), partners in the German Center for Diabetes Research (DZD), have now pinpointed a mechanism that leads to so-called steroid diabetes. Their findings have been published in Nature Communications.”Glucocorticoids such as cortisone have been used to treat inflammatory diseases such as asthma or rheumatism for many decades, and they are the most commonly prescribed anti-inflammatory drugs,” explains Prof. Henriette Uhlenhaut, Group Leader at the Institute for Diabetes and Obesity (IDO) at the Helmholtz Zentrum München and the Gene Center of the LMU. “They are also frequently used in autoimmune diseases, organ transplantations and cancer. It is estimated that between one and three percent of the Western population are currently receiving these drugs – which corresponds to more than one million Germans alone.”Related StoriesIt is okay for women with lupus to get pregnant with proper care, says new studyChaos in the house and asthma in children – the connectionSugary drinks linked to cancer finds studyHowever, although glucocorticoids are prescribed for a wide range of conditions, their use is limited by the various side effects – including unwanted metabolic effects – that can occur during treatment. Once the glucocorticoids bind to their receptor inside the cell, the receptor starts switching numerous genes on and off. “These include various metabolic genes, which can consequently cause so-called steroid diabetes,” Henriette Uhlenhaut explains.In the current study, her team – together with colleagues from the Max Delbrück Center for Molecular Medicine in Berlin, the Salk Institute in San Diego and the University of Freiburg – set out to identify the exact sequence of events that occurs once the steroids bind their receptor.”What struck us most was the E47 transcription factor, which – along with the glucocorticoid receptor – is responsible for the changes in gene expression, particularly in liver cells,” explains Charlotte Hemmer, a doctoral candidate at the IDO and first author of the current study. “We were able to identify the underlying pathway by conducting genome-wide analyses and genetic studies.”In order to corroborate their findings, the scientists then proceeded to examine a preclinical model lacking the E47 gene. “The loss of E47 actually protected against the negative impact of glucocorticoids, while an intact E47 gene led to metabolic changes such as high blood sugar, elevated blood fat levels or a fatty liver as a response to steroid treatment,” Charlotte Hemmer adds.Since the components of the newly discovered mechanism are also conserved in humans, Henriette Uhlenhaut and her team, along with their clinical cooperation partners, would now like to find out whether their results can be translated to human studies. “If this is the case, it could open up new opportunities for therapeutic intervention and the use of safer immuno-suppressants in order to combat the side effects of steroid therapy.” Source:https://www.helmholtz-muenchen.de/en/press-media/press-releases/all-press-releases/press-release/article/45810/index.html
After a patient is admitted, an assigned bedside nurse reviews any new medications with the patient, family member, or caregiver, including what they are used for and any side effects of that particular medication. “This can be easily done through patient medication cards that are premade and ready to go,” See said. Once the discharge medications have been prescribed by the physician, the cardiology nurse navigator asks the patient to write out medication information on a visual aid form called a medication log. This include the names of their discharge medications, what the medications are used for, dose, frequency and what time of day the medications should be taken. See said, “This can be done in conjunction with the floor pharmacist’s instructions at discharge or done separately depending on similar availability.” Next, the floor pharmacist educates the patient in greater depth about their medications, explaining potential side effects and any drug interactions, what to do if a dose is missed and offering any other needed instructions. After discharge, the patient will receive a transition of care phone call within 48 hours from a care coordinator or the nurse navigator. This call includes medication teach back, which requires the patient to read back from memory or read from their prescription bottles the name and usage of their medication. At the patient’s first outpatient cardiac rehab appointment, they are asked to place a check mark by their current medications from a list of common cardiac medications. This helps ensure they are knowledgeable about their medications. Reviewed by James Ives, M.Psych. (Editor)Mar 14 2019Patients understanding their medications and taking them as instructed are important parts of improving the care and outcomes of heart attack patients, as well as potentially reducing avoidable readmissions, according to research presented at the ACC Quality Summit in New Orleans.A heart attack is typically an unexpected event, which can leave patients overwhelmed by new medications, clinicians and other additions to their health care upon release from the hospital. When patients are discharged from the hospital, hospital staff educate them about their medications. However, many patients have difficulty understanding and following these instructions.A new quality improvement plan, developed at Olathe Medical Center in Olathe, Kansas, and initiated as part of the American College of Cardiology’s Patient Navigator Program: Focus MI, showed promising results and shed light on how to approach the issue. The study group considered the patient perspective on the hospital discharge and follow-up experience when developing solutions.”When patients leave a hospital, they often feel there has been little preparation for the discharge plan of care,” said Tara See, RN, BSN, Olathe Medical Center and a leader in the initiative. “Another complaint is that follow-up care is not well established at discharge, there is limited communication with providers receiving them after hospitalization, medication reconciliation and instructions may be hard to understand, and expectations are unclear regarding their recovery and needs when they are discharged.”In April 2018, an interdisciplinary team at Olathe Medical Center, including an assigned bedside RN, cardiology nurse navigator, floor pharmacists and outpatient cardiac rehab staff, established and implemented the following medication education communication process: Related StoriesChildren’s Colorado granted IAC’s Cardiovascular Catheterization accreditationStudy: Two-thirds of pneumonia patients receive more antibiotics than they probably needHome-based support network helps stroke patients adjust after hospital dischargeUsing the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey–a satisfaction survey required by the Centers for Medicare and Medicaid Services for all U.S. hospitals, the study group found the hospital’s HCAHPS scores for medication understanding increased by 10 percent between quarter one and quarter two in 2018 following program implementation. Additionally, before plan implementation, the 2018 quarter one unadjusted readmission rate was 8.2 percent. Since implementation, the quarter two rate went down to 3.4 percent and quarter three was 3.6 percent.”We realize improving medication understanding is only part of what hospitals need to do to help reduce readmissions,” See said. “We are also continuing to focus on other goals, such as increasing risk assessment and appropriate interventions placed on high risk patients. We believe this will optimize our process and further decrease readmissions.”Source: http://www.acc.org/
Reviewed by James Ives, M.Psych. (Editor)Mar 19 2019University of Cincinnati research on adolescent use of electronic cigarettes was featured prominently at the American Academy of Health Behavior 2019 Annual Scientific Meeting on Monday, March 11, in Greenville, South Carolina.”Electronic Cigarette Acquisition Means Among Adolescent Daily Users” earned Ashley Merianos, an assistant professor with UC”s School of Human Services, the 2019 Judy K. Black Award, which is presented by the AAHB in recognition of early-career health behavior research that is innovative and rigorous and that makes an important contribution to science or practice.Merianos’ research is a reflection of UC’s commitment to solving urban issues related to health and well-being, prevention, quality care, researching the next cure, equality in access and talent development. Urban Health and Urban Impact are key components of the university’s strategic direction, Next Lives Here.Merianos performed a secondary analysis of the 2016 National Youth Tobacco Survey and found that of 1,579 adolescents between the ages of 12 and 17 who had admitted to using electronic cigarettes within the last 30 days of the survey, 13.6 percent were daily users. Her research further found that those daily users were far more likely to obtain their electronic cigarettes and accessories from commercial sources than their non-daily using counterparts.Adolescents for whom electronic cigarette use was a daily habit were 5.2 times more likely to buy their e-cigarettes from a drug store, 4.4 times more likely to get them from a vape shop, and 3.3 times more likely to purchase them from a mall kiosk.Daily users were also more likely to purchase their e-cigarettes and vaping supplies online, albeit to a lesser degree; they were 2.5 times more likely to make online purchases than non-daily users. “The internet is very hard to regulate, especially for e-cigarette sales,” Merianos says.Related StoriesResearchers identify gene mutations linked to leukemia in children with Down’s syndromeNew therapeutic food boosts key growth-promoting gut microbes in malnourished childrenDaily intake for phosphates in infants, children can exceed health guidance valuesConversely, non-daily electronic cigarette users were found to be slightly more likely to turn to their friends or family members to obtain vaping products.Merianos recommends that local and state governments adopt 21 as the age of legal purchase to prevent adolescents from getting them, as well as restricting e-cigarette sales from commercial and Internet sources. “We need to inform parents and community members about where their children are getting e-cigarettes from so that they can act as gatekeepers to prevent their children from obtaining these products,” Merianos says. “Also, we need tobacco-use prevention programs to add information on e-cigarettes.”Merianos, who is also an affiliate member of the Division of Emergency Medicine at Cincinnati Children’s Hospital Medical Center, gave an oral presentation of her research at the AAHB conference on Monday, March 11, and a poster presentation the following day.The early-career award from the AAHB is the latest accolade for Merianos, who has garnered national and international media attention for her research on child secondhand and thirdhand smoke exposure. Her work has been featured in online and print media outlets including The New York Times, ABC News and Yahoo News. Merianos has received early career awards from UC and professional organizations.Source: https://www.uc.edu/news/articles/2019/03/n2072609.html
Source:http://www.endocrine.org/ Treating postmenopausal women at high risk of fractures, especially those who have experienced a recent fracture, with pharmacological therapies, as the benefits outweigh the risks. Prescribing initial treatment with bisphosphonates to reduce fracture risk. Reassessing fracture risk after three to five years in women taking bisphosphonates. Women who remain at high risk of fractures should continue therapy, while those who are at low-to-moderate risk of fractures should be considered for a “bisphosphonate holiday.” Using denosumab as an alternative to bisphosphonates for the initial treatment of high-risk individuals. Reviewed by Alina Shrourou, B.Sc. (Editor)Mar 25 2019The benefits of treating osteoporosis in postmenopausal women outweigh the perceived risks, according to a Clinical Practice Guideline issued today by the Endocrine Society. The Society introduced the guideline during a news conference on Monday at ENDO 2019, its annual meeting in New Orleans, La.The guideline, titled “Pharmacological Management of Osteoporosis in Postmenopausal Women: An Endocrine Society Clinical Practice Guideline,” was published online and will appear in the May 2019 print issue of The Journal of Clinical Endocrinology & Metabolism (JCEM), a publication of the Endocrine Society. The guideline provides evidence for the benefits of treating postmenopausal women with osteoporosis. The recommendations cover the newest, most effective medication options and answer patient questions regarding the duration of therapy and monitoring.One in two postmenopausal women will break a bone due to osteoporosis in their lifetime, making them at high risk for subsequent fractures, yet many of these women do not receive treatment. With ongoing reports of atypical femoral fractures and osteonecrosis of the jaw, patients and providers are uncertain about the benefits and risks of treating osteoporosis. In fact, there has been a decline in the use of bisphosphonates and an increase in hip fractures among postmenopausal women.”There is a considerable gap in the treatment of osteoporosis. Most women will not take anti-osteoporosis therapies despite their efficacy, and those that do often stop. As a result, the rate of hip fractures has leveled off and may be increasing. In addition, bone density screening has declined precipitously,” said Clifford J. Rosen, M.D., director, Center for Clinical and Translational Research at the Maine Medical Center Research Institute in Scarborough. Rosen chaired the writing committee that developed the guideline.”We hope our guideline will not only improve patient care but provide confidence in treatment,” he said.Related StoriesTop four things seniors need to know to have a safe and healthy summerMultifunctional nanoparticles could revolutionize treatments for complex bone diseasesVitamin D supplementation may not reduce the risk of heart diseaseRecommendations from the guidelines which were derived from two evidence-based reviews include: Other members of the Endocrine Society writing committee that developed this guideline include: Richard Eastell of the University of Sheffield in Sheffield, United Kingdom; Dennis M. Black of the University of California San Francisco in San Francisco, Calif.; Angela M. Cheung of University of Toronto in Toronto, Canada; M. Hassan Murad of the Mayo Clinic Evidence Based Practice Center in Rochester, Minn.; and Dolores Shoback of the San Francisco Veterans Affairs Medical Center in San Francisco, Calif.The Society established the Clinical Practice Guideline Program to provide endocrinologists and other clinicians with evidence-based recommendations in the diagnosis, treatment, and management of endocrine-related conditions. Each guideline is created by a writing committee of topic-related experts in the field. Writing committees rely on evidence-based reviews of the literature in the development of guideline recommendations. The Endocrine Society does not solicit or accept corporate support for its guidelines. All Clinical Practice Guidelines are supported entirely by Society funds.
Reviewed by James Ives, M.Psych. (Editor)May 23 2019People born in rural communities in the South, especially in southern Appalachia and the Mississippi Delta, may live shorter and less healthy lives than their counterparts elsewhere in the country, in part due to a high burden of heart, lung, blood and sleep disorders (HLBS). Within the same Southern regions, however, there are counties with very low risk of disease that have profiles of economic disadvantages, race/ethnicity, and rurality similar to those considered high risk.In an effort to understand why certain factors amplify risk in some rural counties and what renders some communities more resilient, researchers will be studying 4,000 multi-ethnic participants from 10 of the low-income rural counties in Kentucky, Alabama, Mississippi and Louisiana recruited into a new longitudinal cohort study. The Risk Underlying Rural Areas Longitudinal Study (RURAL) will allow researchers to learn what causes the burden of HLBS disorders in these communities and how to alleviate them.This multi-site prospective cohort study will be coordinated by Boston University School of Medicine’s Vasan Ramachandran, MD, FAHA, FACC, principal investigator and Boston University director of the renowned Framingham Heart Study, with which he has been affiliated for more than 20 years. Over fifty investigators at 16 institutions will participate in this six-year, $21.4 million study funded by the National Heart, Lung, and Blood Institute, part of the National Institutes of Health.Using a self-contained mobile examination unit, ‘a research center on wheels,’ a transdisciplinary team will conduct an approximately four-hour detailed baseline examination on the study participants. Familial, lifestyle and behavioral factors, along with medical history including risk for HLBS disorders will be recorded. Environmental and economic factors also will be studied and standard and novel risk factors for HLBS disorders will be assayed. Investigators will use smart phones and wearable activity monitors in order to help collect health and lifestyle information of the participants. The rural health challenge in the South does not spare any race or ethnicity. These high risk and economically disadvantaged rural communities are vulnerable to clusters of multiple health problems. We aim to understand the rural health challenges in the South and share our findings with and offer health education to these rural communities.”Vasan Ramachandran, Boston University School of Medicine Stephanie Boone, PhD, MPH, University of Louisville (Kentucky); Stephanie Broyles, PhD, LSU’s Pennington Biomedical Research Center; Ervin Fox, MD, MPH, University of Mississippi Medical Center; Suzanne Judd, PhD, University of Alabama at Birmingham and Paul Targonski, MD, PhD, University of Virginia at Charlottesville will play a central role in participant recruitment, retention, follow-up, data collection, return of results, community engagement and education.Source: Boston University School of Medicine
Related StoriesOlympus launches next-generation X Line objectives for clinical, research applicationsScientists develop universal FACS-based approach to heterogenous cell sorting, propelling organoid researchOlympus Europe and Cytosurge join hands to accelerate drug development, single cell researchThe researchers worked to establish whether blocking the nuclear cytoplasmic transport process would slow the growth of myelofibrosis cells. To accomplish this, they generated a type of mouse with a specific mutation that leads to symptoms very similar to those experienced by myelofibrosis patients. When these mice were treated with the newly tested drug selinexor they responded just as well as those treated with ruxolitinib, and importantly, selinexor actually appeared to reduce the percentage of malignant cells.Based on these findings, the researchers designed a new clinical trial to study the effectiveness of selinexor in people with myelofibrosis. The clinical trial of selinexor in the treatment of relapsed/refractory myelofibrosis is now open at HCI. The researchers aim to enroll at least 24 patients who will receive the treatment in a setting that will allow for rigorous examination of any clinical benefit and monitoring of side effects. If this early trial indicates positive outcomes for patients, more extensive studies involving additional sites and more patients will be planned. Our results opened a new window for therapeutic intervention. By wonderful coincidence, selinexor, an inhibitor of this specific mechanism, is in clinical trials for certain blood cancers and now will be tested specifically in myelofibrosis patients.” Reviewed by James Ives, M.Psych. (Editor)Jun 20 2019Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) discovered in laboratory studies that an experimental drug called selinexor may block a crucial survival pathway exploited by myelofibrosis cells. Their study was published in Clinical Cancer Research, a journal of the American Association of Cancer Research. Based on these findings, they designed a clinical trial now open at HCI to examine this drug’s effectiveness in patients with myelofibrosis (National Clinical Trial 03627403)Myelofibrosis is a rare cancer that prevents the bone marrow from making healthy blood cells. Life expectancy varies, but most patients will not live beyond five years after the diagnosis. HCI treats about 25 newly diagnosed myelofibrosis patients a year.Srinivas Tantravahi, MBBS, MRCP, a physician-scientist at HCI and assistant professor of medicine at the U of U, takes care of patients with myelofibrosis, and says it is a very debilitating disease. “Essentially, it’s a bone marrow failure. The patient will experience severe symptoms including enlargement of the spleen, anemia, pain in the belly, fatigue, and a very poor quality of life,” says Tantravahi, who was part of the study team. “A stem cell transplant can potentially cure the disease, but most patients diagnosed with myelofibrosis are older or not healthy enough to undergo the weeks-long procedure.”A drug called ruxolitinib is the current primary treatment for myelofibrosis patients who are not healthy enough to receive a stem cell transplant. This drug can decrease spleen size, improve symptoms and improve quality of life, but it does not typically reduce the percentage of malignant cells. The lack of available therapies for myelofibrosis patients motivated the research team at HCI to look for new avenues for treatment. “Ruxolitinib is a fine drug, but its effects are mostly short-lived. And, until now, there were no other options for patients who aren’t healthy enough for a stem cell transplant,” said Dongqing Yan, PhD, a research associate in the Deininger/O’Hare Lab at HCI and lead author on the study.The team discovered myelofibrosis cells are highly sensitive to blockade a cellular process called nuclear-cytoplasmic transport.Anthony Pomicter, MS, manager of the Deininger/O’Hare lab explains: Source:Huntsman Cancer Institute The ability to advance a study like this from bench to bedside – from first discovery in a laboratory setting to first in the world clinical trial – is a credit to the unique environment at HCI. Myelofibrosis is a rare cancer, and it makes life miserable for those affected. It is extremely important that HCI and other institutions continue to push the discovery effort in all types of cancer, including rare diseases like myelofibrosis, so can we bring better treatment options to our patients.”Michael Deininger, MD, PhD, HCI senior director of transdisciplinary research and professor of medicine at the U of U, and senior author on the study
The social media giant said it did not know the data was being used in a political campaign This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Damian Collins, the chairman of the House of Commons digital, culture and media committee, said that the seriousness of the allegations meant it was “appropriate” for Zuckerberg to offer an explanation himself, whether in person or via videolink.In a letter published by the committee on Tuesday, a senior British Facebook executive offered to send chief technology office Mike Schroepfer or chief product officer Chris Cox to London next month.”We’d be very happy to invite Mr Cox to give evidence,” Collins said at the start of a committee hearing on Tuesday.”However we would still like to hear from Mr Zuckerberg as well. “We will seek to clarify with Facebook whether he is available to give evidence or not, because that wasn’t clear from our correspondence, and if he is available to give evidence then we would be happy to do that either in person or via video link if that would be more convenient for him.”In the letter to Collins, Rebecca Stimson, head of public policy for Facebook UK, wrote: “Facebook fully recognizes the level of public and parliamentary interest in these issues and support your belief that these issues must be addressed at the most senior levels of the company by those in an authoritative position to answer your questions.”As such Mr Zuckerberg has personally asked one of his deputies to make themselves available to give evidence in person to the committee.”She said either Schroepfer or Cox could attend “straight after the Easter parliamentary recess”, meaning April 16 at the earliest.The committee’s request to Facebook followed allegations that data from up to 50 million users was harvested by a British company, Cambridge Analytica, for use in election campaigns, namely that of US President Donald Trump in 2016.The social media giant said it did not know the data was being used in a political campaign, although it did allow an academic researcher to create an app that picked up the information from users and their friends.In the letter, Stimson revealed that Facebook was working with regulators around the world to assess how many people in each country were affected.”We can now confirm that around one percent of the global downloads of the app came from users in the EU, including the UK,” she wrote. British MPs renewed a demand on Tuesday to interview Facebook chief Mark Zuckerberg personally over a data privacy row, after he responded to an earlier request by offering to send one of his deputies. Explore further © 2018 AFP UK MPs ask Facebook’s Zuckerberg to testify on data row Citation: UK MPs demand Zuckerberg testify on data row after he offers deputy (2018, March 27) retrieved 18 July 2019 from https://phys.org/news/2018-03-uk-mps-demand-zuckerberg-testify.html
Tesla CEO Elon Musk has rebuffed a shareholder attempt to overhaul the electric car maker’s board and strip him of his role as chairman, despite worries about the company’s shaky finances and inability to meet its production goals for its first mass-market sedan. Explore further Tesla reveals plans to build cars in Shanghai In this Dec. 2, 2015, file photo, Tesla Motors Inc. CEO Elon Musk delivers a speech at the Paris Pantheon Sorbonne University as part of the United Nations Climate Change Conference in Paris. Musk has rebuffed a shareholder attempt to overhaul the electric car maker’s board and strip him of his role as chairman, despite worries about the company’s shaky finances and inability to meet its production goals for its first mass-market sedan. All three directors seeking to remain on Tesla’s nine-member board were re-elected during the company’s annual meeting Tuesday, June 5, 2018, as most shareholders opposed a rebellion seeking to remove them. (AP Photo/Francois Mori, File) All three directors seeking to remain on Tesla’s nine-member board were re-elected during the company’s annual meeting held Tuesday in Mountain View, California.Directors Antonio Gracias, James Murdoch and Elon’s brother, Kimbal Musk, won by “a wide margin,” according to Tesla. CtW Investment Group, an activist firm that represents labor union pension funds, had spearheaded a rebellion seeking to oust the trio from the board on the grounds that they didn’t know about the auto industry at a critical time in Tesla’s existence.The company said a “supermajority” of shareholders also rejected a proposal to force Musk to step down as Tesla’s chairman, a position he has held since 2004—four years before he also assumed the CEO job.The precise voting totals will be disclosed within the next few days.Elon Musk holds a 22 percent stake in Tesla, increasing the degree of difficulty for shareholders trying to challenge his authority. After the results were announced, he sought to reassure shareholders attending the meeting and others watching on a webcast.After describing the past few months as among the most “hellish” in his life, Musk said he expected Tesla to post a quarterly profit during the July-September period. That’s something the Palo Alto, California, company has rarely pulled off in a 15-year history marked by steady losses while investing heavily in its technology and manufacturing plants.Tesla has been burning through so much cash—more than $1 billion during the first three months of this year alone—that investors have been worrying it will have to sell more stock or add to its already hefty debt load to raise enough money to survive.After conceding that “staying alive” is difficult in the auto industry, Musk told shareholders that Tesla will be “cash flow positive” during the second half of this year. If Musk is correct, the prediction will translate into Tesla bringing in more cash than it’s spending in both the third and fourth quarters.To do that, Tesla will probably have to meet Musk’s manufacturing goals for its Model 3, a sedan with a starting price tag of $35,000 that represents the company’s attempt to reach a mass market. Tesla still needs to more than double its recent production rate to reach Musk’s target of delivering 5,000 Model 3s per week. Musk reiterated previous predictions that that will happen during the second half of this year.Tesla’s stock gained about 1 percent to $294.35 in Tuesday’s extended trading. That’s about 24 percent below its all-time high set in September at $389.61 © 2018 The Associated Press. All rights reserved. Citation: Tesla shareholders reject bid to strip Musk of chairman role (2018, June 6) retrieved 18 July 2019 from https://phys.org/news/2018-06-tesla-shareholders-musk-chairman-role.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
The study found that for the same median household income:black-majority census tracts—or neighborhoods—have installed 69 percent less rooftop PV than census tracts (neighborhoods) where no single race or ethnicity makes up the majority (no-majority); and Hispanic-majority census tracts have installed 30 percent less rooftop PV than no-majority census tracts. Meanwhile, white-majority census tracts have installed 21 percent more rooftop PV than no-majority census tracts.When correcting for home ownership, black- and Hispanic-majority census tracts have installed less rooftop PV compared to no-majority tracts by 61 percent and 45 percent, respectively, while white-majority census tracts installed 37 percent more. Although the popularity of rooftop solar panels has skyrocketed because of their benefits to consumers and the environment, the deployment has predominantly occurred in white neighborhoods, even after controlling for household income and home ownership, according to a study by researchers from Tufts University and the University of California, Berkeley, published today in the journal Nature Sustainability. Team locates nearly all US solar panels in a billion images with machine learning More information: Deborah A. Sunter et al, Disparities in rooftop photovoltaics deployment in the United States by race and ethnicity, Nature Sustainability (2019). DOI: 10.1038/s41893-018-0204-z Tufts University and the University of California, Berkeley, found that the deployment of rooftop solar panels has predominantly occurred in white neighborhoods, even after controlling for household income and home ownership, according to a study by researchers from Credit: Deborah Sunter, Ph.D., a professor of mechanical engineering at the School of Engineering at Tufts, and the study’s lead author. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Citation: Racial inequality in the deployment of rooftop solar energy in the US (2019, January 10) retrieved 17 July 2019 from https://phys.org/news/2019-01-racial-inequality-deployment-rooftop-solar.html The study’s authors said more research is needed to help determine the root causes of the differences. They noted that the findings could be useful in developing better and more inclusive energy infrastructure policy and outcomes, including as part of the evolving ‘Green New Deal’ and programs at the state and federal level.”Our work illustrates that while solar can be a powerful tool for climate protection and social equity, a lack of access or a lack of outreach to all segments of society can dramatically weaken the social benefit,” said Daniel Kammen, Ph.D., former science envoy for the U. S. State Department, and current professor and chair of the Energy and Resources Group, professor in the Goldman School of Policy, and professor of Nuclear Engineering at UC Berkeley. Both Sunter and Kammen have been fellows of the Berkeley Institute for Data Science (BIDS), and Castellanos is a fellow at UC Berkeley´s Data for Social Sciences Lab (D-Lab). Tufts University and the University of California, Berkeley, found that the deployment of rooftop solar panels has predominantly occurred in white neighborhoods. Here the analysed region (yellow) contains 58% of the national technical potential for rooftop PV annual energy generation. Credit: Deborah Sunter, Ph.D., a professor of mechanical engineering at the School of Engineering at Tufts, and the study’s lead author. Journal information: Nature Sustainability Explore further Provided by Tufts University While solar energy is a popular, cost-effective, sustainable source of energy that can be deployed at large, utility-scale projects as well as on individual rooftops, deployment of rooftop solar has been uneven.”Solar power is crucial to meeting the climate goals presented by the Intergovernmental Panel on Climate Change, but we can and need to deploy solar more broadly so that it benefits all people, regardless of race and ethnicity,” said Deborah Sunter, Ph.D., a professor of mechanical engineering at the School of Engineering at Tufts, and the study’s lead author. “Solar energy can be a resource for climate protection and social empowerment.”Researchers combined data from Google’s Project Sunroof on existing rooftop solar installations across the United States with demographic data, including household income, home ownership, and ethnicity and race, from the U.S. Census Bureau’s American Community Survey. The Project Sunroof data includes information on more than 60 million rooftops, and almost 2 million solar installations.”Advances in remote sensing and in ‘big data’ science enable us not only to take a unique look at where solar is deployed but also to combine that with census and demographic data to chart who gets to benefit from the solar energy revolution,” said Sergio Castellanos, Ph.D., a research faculty at UC Berkeley’s Energy and Resources Group and the California Institute for Energy and Environment (CIEE). “This information allows us to think more deeply about the effectiveness of current policies and approaches to accelerating solar PV (photovoltaics) deployment.”
A woman in England died after falling onto a reusable metal straw, which pierced her head, and the tragic accident has renewed debate over bans on plastic straws, according to news reports. The woman, 60-year-old Elena Struthers-Gardner, was carrying a glass with a 10-inch-long stainless-steel straw when she fell and the straw impaled her eye, causing fatal brain injuries, according to the Daily Echo, a British newspaper. Struthers-Gardner had scoliosis, or a sideways curvature of the spine, which made her prone to falls. Struthers-Gardner died in November, and a coroner’s report on her death was released this week, according to The New York Times. The report called her death an accident.Headbutting Tiny Worms Are Really, Really LoudThis rapid strike produces a loud ‘pop’ comparable to those made by snapping shrimps, one of the most intense biological sounds measured at sea.Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Why Is It ‘Snowing’ Salt in the Dead Sea?01:53 facebook twitter 发邮件 reddit 链接https://www.livescience.com/65925-metal-straw-death.html?jwsource=cl已复制直播00:0000:3500:35 Several U.S. cities and states have already banned plastic straws to reduce the plastic entering the environment, and a similar ban is set to take effect in England in April 2020, the Times reported. But the bans have sparked concern among people with disabilities and their advocates, who say the bans make straws unavailable for those with disabilities who rely on straws to drink, according to NPR. In addition, the rigidity of reusable metal straws may pose safety risks. “I just feel that in the hands of mobility-challenged people like Elena [Struthers-Gardner], or children, or even able-bodied people losing their footing, these [straws] are so long and very strong,” Mandy Struthers-Gardner, Elena’s wife, said in a statement, the Daily Echo reported. “Even if they don’t end a life, they can be very dangerous.” In 2016, Starbucks recalled 2.5 million stainless-steel straws due to reports of young children who experienced mouth lacerations from using the straws, according to U.S. Consumer Product Safety Commission. Brendan Allen, the assistant coroner involved in Struthers-Gardner’s case, also warned about the potential dangers of metal straws. “Clearly, great care should be taken when using these metal straws. There is no give in them at all,” Allen said. He added that in this case, the metal straw may have been particularly hazardous because it was used with a lid that prevented the straw from moving. “It seems to me these metal straws should not be used with any form of lid that holds them in place,” Allen said. “It seems the main problem here is if the lid hadn’t been in place the straw would have moved away.” In Images: The Great Pacific Garbage Patch In Photos: World’s 10 Most Polluted Places Top 10 Craziest Environmental Ideas Originally published on Live Science.by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeVikings: Free Online GamePlay this for 1 minute and see why everyone is addictedVikings: Free Online GameUndoTruthFinder People Search SubscriptionOne Thing All Liars Have in Common, Brace YourselfTruthFinder People Search SubscriptionUndoGundry MD Total Restore SupplementU.S. Cardiologist: It’s Like a Pressure Wash for Your InsidesGundry MD Total Restore SupplementUndoAncestryThe Story Behind Your Last Name Will Surprise YouAncestryUndoDirectExposeThis Baby Elephant Decided To Spend His Last Days Alongside This CreatureDirectExposeUndoScience101This Is The Smartest Dog Breed According To VeterinariansScience101Undo
COMMENT COMMENTS Siddaramaiah April 01, 2019 state politics Published on Mocks at ‘acche din’ & ‘chowkidar’ campaign, reminds BJP of what happened to ‘India Shining’ SHARE Allaying doubts over the survival of the JD(S)-Congress coalition government in Karnataka after the Lok Sabha elections, former Karnataka Chief Minister Siddaramaiah has said the coalition government will remain strong after the elections. Interacting with reporters at a ‘Meet the Press’ programme organised by Bangalore Reporters’ Guild and the Press Club of Bangalore on Monday, he said, “Looking at the Bharatiya Janata Party’s futile efforts to take out the government, it is clear the HD Kumaraswamy government will complete its term”. On the BJP’s attempts to poach into Congress ranks, Siddaramaiah said, “People committed to principles will not desert the party. It is only people who have no belief in democracy or those having no ideological base that do party-hopping.” Modi will not be PM“The BJP will not win. Modi will not be Prime Minister again,” said Siddaramaiah. “The BJP cannot repeat its stellar performance in Uttar Pradesh, Bihar, and Gujarat again as it did in the previous Lok Sabha elections.”“Looking at the regional pre-election alliance and the possibility of post-election tie-ups like the Samajwadi Party and Bahujan Samaj Party alliance in UP and Rashtriya Janata Dal and Congress tie-up in Bihar, the saffron party will be trounced this time,” he added. No lesson learntTaking a dig at the campaigns initiated by the BJP in the last six months, Siddaramaiah said that without learning the lessons from the past, they are again talking of ‘acche din’ and chowkidar. “I just want to remind them of what happened to the famous ‘India Shining’ during Vajpayee rule. “They got defeated by anti-poor policies I don’t know where it shined. If it had really shone, there was no need for any welfare schemes.” Siddaramaiah said the BJP leaders, without looking at the Congress’ track record of serving the poor, are criciticsing and are slamming our poll promise of Minimum Income Guarantee Scheme (Nyunatam Aay Yojana-NYAY) that will cost ₹3.26 lakh crore to the national exchequer.“They mock our scheme of giving ₹3.5 lakh crore to the poor people and speak low about it. The very fact that they are opposing this programme, they are anti-poor. They cannot stand with the economically weaker sections. There are no such instances whether be it former prime minister Vajpayee or Modi’s five-year term,” Siddaramaiah said . SHARE SHARE EMAIL Elections 2019 Karnataka
Published on June 24, 2019 COMMENT environmental issues Noting that States have been demanding a reduction or an alteration in the Eco-Sensitive Area (ESA) of Western Ghats, the Centre has started fresh discussions to finalise notification on declaration of ESA. Minister of Environment Prakash Javadekar told the Lok Sabha on June 21 that considering that the validity of the latest draft Notification was March 31, 2019, fresh discussion has been started with the States. “Fresh discussion to finalise the notification to declare the ESA of the Western Ghats has already been initiated with the States and a meeting was held on February 15,” he said.Main demands On the main demands of individual States, the Minister replied in a written answer, “in general, the demand from the States is to reduce/alter the ESA as recommended by the high level working group (HLWG)”.The HLWG headed by K Kasturirangan had delineated a contiguous ESA of 59,940 sq km in the Western Ghats region spread over six States — Kerala, Tamil Nadu, Karnataka, Goa, Maharashtra and Gujarat — and recommended specific measures for conservation.The process to conserve and protect the Western Ghats was started 2010 with the setting of the Western Ghats Ecology Expert Panel (WGEEP) and followed by the constitution of HLWG in 2012. The Ministry of Environment, Forest and Climate Change had issued the first draft notification in February 2014.Prohibited activitiesThe government has prohibited activities having interventionist and destructive impacts on natural ecosystems of the ESA. These activities include mining, quarrying and sand mining and setting up of thermal power plants. SHARE SHARE EMAIL COMMENTS SHARE Minister of Environment Prakash Javadekar – THE HINDU